|
|
L-kynurenine + H2O <=> H+ + L-alanine + anthranilate
|
3.7.1.3
kynureninase
|
–
|
BMK
|
|
BRENDA:
BR29549
KEGG:
R00987
MetaCyc:
KYNURENINASE-RXN
SABIO-RK:
1281
|
|
|
|
chorismate + L-glutamine <=> H+ + anthranilate + L-glutamate + pyruvate
|
4.1.3.27
anthranilate synthase
|
–
|
BMK
|
|
BRENDA:
BR3373
KEGG:
R00986
MetaCyc:
ANTHRANSYN-RXN
SABIO-RK:
1280
|
|
|
|
H+ + anthranilate + O2 + NADPH <=> NH3 + NADP+ + 2,3-Dihydroxybenzoate
|
1.14.13.35
anthranilate 3-monooxygenase (deaminating)
|
–
|
K
|
|
BRENDA:
BR40420
KEGG:
R00980
MetaCyc:
1.14.13.35-RXN
|
|
|
|
anthranilate + O2 + NADPH + H+ <=> catechol + CO2 + NH3 + NADP+
|
1.14.12.1
anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
|
–
|
MK
|
|
BRENDA:
BR40446
KEGG:
R00825
MetaCyc:
1.14.12.1-RXN
|
|
|
|
anthranilate + O2 + NADH + H+ <=> catechol + CO2 + NH3 + NAD+
|
1.14.12.1
anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
|
–
|
K
|
|
BRENDA:
BR40446-a
KEGG:
R00823
MetaCyc:
1.14.12.1-RXN_WOP
|
|
|
|
2,3-Dihydroxyindole + O2 <=> H+ + anthranilate + CO2
|
1.13.11.23
2,3-dihydroxyindole 2,3-dioxygenase
|
–
|
K
|
|
BRENDA:
BR40482
KEGG:
R00983
MetaCyc:
23-DIHYDROXYINDOLE-23-DIOXYGENASE-RXN
|
|
|
|
S-adenosyl-L-methionine + anthranilate <=> H+ + S-adenosyl-L-homocysteine + N-Methylanthranilate
|
2.1.1.111
anthranilate N-methyltransferase
|
–
|
MK
|
|
BRENDA:
BR43871
KEGG:
R00984
MetaCyc:
ANTHRANILATE-N-METHYLTRANSFERASE-RXN
|
|
|
|
anthranilate + benzoyl-CoA <=> N-benzoylanthranilate + CoA
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
M
|
|
BRENDA:
BR44005
KEGG:
R02453
MetaCyc:
ANTHRANILATE-N-BENZOYLTRANSFERASE-RXN
|
|
|
|
N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate <=> anthranilate + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.18
anthranilate phosphoribosyltransferase
|
–
|
BMK
|
|
BRENDA:
BR47560
KEGG:
R01073
MetaCyc:
PRTRANS-RXN
SABIO-RK:
1341
|
|
|
|
anthranilate + malonyl-CoA <=> N-malonylanthranilate + CoA
|
2.3.1.113
anthranilate N-malonyltransferase
|
–
|
|
|
BRENDA:
BR47640
KEGG:
R00989
MetaCyc:
ANTHRANILATE-N-MALONYLTRANSFERASE-RXN
|
|
|
|
anthranilate + CoA + ATP <=> 2-aminobenzoyl-CoA + AMP + diphosphate
|
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.25
benzoate---CoA ligase
6.2.1.32
anthranilate---CoA ligase
|
–
–
–
|
BMK
|
|
BRENDA:
BR48384
KEGG:
R00982
MetaCyc:
AMINOBENZCOALIG-RXN
|
|
|
|
anthranilate + O2 + FADH2 <=> H+ + 3-Hydroxyanthranilate + H2O + FAD
|
1.14.14.8
anthranilate 3-monooxygenase (FAD)
|
–
|
BMK
|
|
BRENDA:
BR49368
KEGG:
R09517
MetaCyc:
RXN-10724
|
|
|
|
(2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> H+ + anthranilate + 2-hydroxy-2,4-pentadienoate
|
3.7.1.13
2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase
|
–
|
MK
|
|
BRENDA:
BR49394
KEGG:
R05365
MetaCyc:
RXN-11543
|
|
|
|
S-adenosyl-L-methionine + ATP + anthranilate + L-phenylalanine <=> cyclopeptine + AMP + diphosphate + S-adenosyl-L-homocysteine + H+
|
6.3.2.40
cyclopeptine synthase
|
–
|
BM
|
|
BRENDA:
BR50555
KEGG:
R10495
MetaCyc:
RXN-13989
|
|
|
|
S-adenosyl-L-methionine + anthranilate <=> O-methyl_anthranilate + S-adenosyl-L-homocysteine
|
2.1.1.273
benzoate O-methyltransferase
2.1.1.274
salicylate 1-O-methyltransferase
2.1.1.277
anthranilate O-methyltransferase
|
–
–
–
|
|
|
BRENDA:
BR50623
KEGG:
R10451
MetaCyc:
RXN-14453
SABIO-RK:
14113
|
|
|
|
anthranilate + N,N-dimethyl-1,4-phenylenediamine + NAD+ <=> H+ + Methyl_red + NADH
|
1.7.1.17
FMN-dependent NADH-azoreductase
1.7.1.6
azobenzene reductase
|
–
–
|
|
|
BRENDA:
BR52233;
BS389170
KEGG:
R12035
MetaCyc:
RXN0-5375
SABIO-RK:
9591
|
|
|
|
H+ + anthranilate <=> aniline + CO2
|
4.1.1.24
aminobenzoate decarboxylase
|
–
|
|
|
BRENDA:
BS1363
KEGG:
R00990
MetaCyc:
RXN-7927
|
|
|
|
UDP-glucose + anthranilate <=> 1-O-anthraniloyl-beta-D-glucose + UDP
|
2.4.1
2.4.1.120
sinapate 1-glucosyltransferase
|
–
–
|
M
|
|
BRENDA:
BS322026
MetaCyc:
RXN-11853
|
|
|
|
N-formylanthranilic_acid + H2O <=> formate + anthranilate
|
3.5.1.9
arylformamidase
|
–
|
K
|
|
BRENDA:
BS140693
KEGG:
R00988
|
|
|
|
chorismate + NH3 <=> anthranilate + pyruvate + H2O
|
4.1.3.27
anthranilate synthase
|
–
|
K
|
|
BRENDA:
BS380574
KEGG:
R00985
SABIO-RK:
1279
|
|
|
|
anthranilate + L-tryptophan + L-alanine + ATP <=> Fumiquinazoline_F + diphosphate + AMP + H2O + H+
|
6.3.2
|
–
|
MK
|
|
KEGG:
R12417
MetaCyc:
RXN-15746
|
|
|
|
acetyl-CoA + anthranilate <=> CoA + N-acetylanthranilate
|
2.3.1.118
N-hydroxyarylamine O-acetyltransferase
2.3.1.5
arylamine N-acetyltransferase
|
–
–
|
|
|
BRENDA:
BS320369
SABIO-RK:
14454
|
|
|
|
anthranilate <=> 2-Formaminobenzoylacetate
|
not assigned
|
–
|
K
|
|
KEGG:
R00991
|
|
|
|
o-Hydroxylaminobenzoate + 2 H+ <=> anthranilate + H2O
|
1.4
|
–
|
K
|
|
KEGG:
R07734
|
|
|
|
anthranilate <=> 4-hydroxyquinolin-2(1H)-one
|
not assigned
|
–
|
|
|
KEGG:
R08473
|
|
|
|
anthranilate + DELTA1-pyrroline <=> vasicine
|
not assigned
|
–
|
|
|
KEGG:
R08477
|
|
|
|
2-Aminobenzaldehyde + O2 + NADH <=> anthranilate + H2O + NAD+
|
1.14.13
|
–
|
|
|
MetaCyc:
RXN-15186
|
|
|
|
2-Aminobenzaldehyde + O2 + NADPH <=> anthranilate + NADP+ + H2O
|
1.14.13
|
–
|
M
|
|
MetaCyc:
RXN-15191
|
|
|
|
L-tryptophan + anthranilate + ATP <=> (R)-benzodiazepinedione + ADP + phosphate + H+
|
6.3.2
|
–
|
M
|
|
MetaCyc:
RXN-15667
|
|
|
|
anthranilate + L-alanine + L-tryptophan + ATP <=> ardeemin_FQ + AMP + diphosphate + H2O + H+
|
6.3.2
|
–
|
M
|
|
MetaCyc:
RXN-15762
|
|
|
|
anthranilate + L-tryptophan + ATP <=> asperlicin_C + AMP + diphosphate + H2O + H+
|
6.3.2
|
–
|
M
|
|
MetaCyc:
RXN-15797
|
|
|
|
anthranilate + L-tryptophan + ATP <=> asperlicin_D + AMP + diphosphate + H2O + H+
|
6.3.2
|
–
|
M
|
|
MetaCyc:
RXN-15798
|
|
|
|
S-adenosyl-L-methionine + anthranilate + O-methyl-L-tyrosine + ATP <=> 4''-methoxycyclopeptine + AMP + diphosphate + S-adenosyl-L-homocysteine + H+
|
6.3.2.40
cyclopeptine synthase
|
–
|
M
|
|
MetaCyc:
RXN-16979
|
|
|
|
o-Hydroxylaminobenzoate + NADPH + H+ <=> anthranilate + H2O + NADP+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8848
|
|
|
|
o-Hydroxylaminobenzoate + NADH + H+ <=> anthranilate + H2O + NAD+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-8848_WOP
|
|
|
|
anthranilate + tetrahydrobiopterin + O2 <=> 3-Hydroxyanthranilate + dihydrobiopterin + H2O
|
1.14.16.3
anthranilate 3-monooxygenase
|
–
|
|
|
BRENDA:
BR40404
|
|
|
|
anthranilate + FADH2 + Cl- + O2 + H+ <=> 2-Amino-5-chlorobenzoate + FAD + 2 H2O
|
1.14.19.58
tryptophan 5-halogenase
1.14.19.59
tryptophan 6-halogenase
|
–
–
|
|
|
BRENDA:
BS443056
|
|
|
|
anthranilate + tetrahydrofolate + O2 <=> 3-Hydroxyanthranilate + 7,8-dihydrofolate + H2O2
|
1.14.16.3
anthranilate 3-monooxygenase
|
–
|
|
|
BRENDA:
BS288192
|
|
|
|
2-aminobenzoyl-CoA + H2O <=> anthranilate + CoA
|
3.1.2.23
4-hydroxybenzoyl-CoA thioesterase
|
–
|
|
|
BRENDA:
BS398635
|
|
|
|
feruloyl-CoA + anthranilate <=> CoA + 4-demethyltranilast
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS420689
|
|
|
|
4-coumaroyl-CoA + anthranilate <=> CoA + N-4-(coumaroyl)anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS320521
|
|
|
|
cinnamoyl-CoA + anthranilate <=> CoA + N-cinnamoylanthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS420489
|
|
|
|
cinnamoyl-CoA + anthranilate <=> CoA + N-cinammoylanthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS320520
|
|
|
|
sinapoyl-CoA + anthranilate <=> CoA + N-sinapoylanthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS421504
|
|
|
|
3-Coumaroyl-CoA + anthranilate <=> CoA + N-(3-hydroxycinnamoyl)-anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS419973
|
|
|
|
2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoic_acid + H2O <=> anthranilate + 2-hydroxy-2,4-pentadienoate
|
3.7.1.13
2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase
3.7.1.8
2,6-dioxo-6-phenylhexa-3-enoate hydrolase
|
–
–
|
|
|
BRENDA:
BS387149
|
|
|
|
2,3-dimethoxycinnamoyl-CoA + anthranilate <=> CoA + N-(2,3-dimethoxycinnamoyl)-anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS419829
|
|
|
|
2,5-dimethoxycinnamoyl-CoA + anthranilate <=> CoA + N-(2,5-dimethoxycinnamoyl)-anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS419839
|
|
|
|
2,4-dimethoxycinnamoyl-CoA + anthranilate <=> CoA + N-(2,4-dimethoxycinnamoyl)-anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS419835
|
|
|
|
4-methoxycinnamoyl-CoA + anthranilate <=> CoA + N-(4-methoxycinnamoyl)-anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS420054
|
|
|
|
2-coumaroyl-CoA + anthranilate <=> CoA + N-(2-coumaroyl)anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS419879
|
|
|
|
3,4,5-trimethoxycinnamoyl-CoA + anthranilate <=> CoA + N-(3,4,5-trimethoxycinnamoyl)-anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS419953
|
|
|
|
isoferuloyl-CoA + anthranilate <=> CoA + 3-demethyltranilast
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS419979
|
|
|
|
2-hydroxybenzoyl-CoA + anthranilate <=> CoA + N-salicylanthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS320522
|
|
|
|
caffeoyl-CoA + anthranilate <=> CoA + N-(3,4-dihydroxycinnamoyl)-anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS420434
|
|
|
|
thiamine + anthranilate <=> 4-methyl-5-(2-hydroxyethyl)-thiazole + 2-[[(4-amino-2-methylpyrimidin-5-yl)methyl]amino]benzoic_acid
|
2.5.1.2
thiamine pyridinylase
|
–
|
|
|
BRENDA:
BS353807
|
|
|
|
3-methoxycinnamoyl-CoA + anthranilate <=> CoA + N-(3-methoxycinnamoyl)-anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS419993
|
|
|
|
2-phenylacetamidobenzoic_acid + H2O <=> phenylacetate + anthranilate
|
3.5.1.11
penicillin amidase
|
–
|
|
|
BRENDA:
BS116025
|
|
|
|
2-Aminobenzaldehyde + O2 <=> anthranilate
|
1.13.11.17
indole 2,3-dioxygenase
|
–
|
|
|
BRENDA:
BS260794
|
|
|
|
indole + O2 <=> anthranilate
|
1.13.11.17
indole 2,3-dioxygenase
|
–
|
|
|
BRENDA:
BS260790
|
|
|
|
2-nitro-5-[(phenylacetyl)amino]-benzoic_acid + H2O <=> phenylacetate + anthranilate
|
3.5.1.11
penicillin amidase
|
–
|
|
|
BRENDA:
BS449261
|
|
|
|
anthranilate + NADH + 2 H+ + O2 <=> 2-Aminophenol + NAD+ + H2O + CO2
|
1.14.13.1
salicylate 1-monooxygenase
|
–
|
|
|
BRENDA:
BS396421
|
|
|
|
anthranilate + NADH + O2 <=> 2-Aminophenol + NAD+ + H2O2 + CO2
|
1.14.13.27
4-aminobenzoate 1-monooxygenase
|
–
|
|
|
BRENDA:
BS288399-a
|
|
|
|
4''-dimethylaminoazobenzene-2-carboxylic_acid + NADH + H+ <=> anthranilate + N,N''-dimethyl-p-phenylenediamine + NAD+
|
1.7.1.6
azobenzene reductase
|
–
|
|
|
BRENDA:
BS403794
|
|
|
|
2-(4-dimethylaminophenylazo)_benzoic_acid + NADH + H+ <=> N,N''-dimethyl-p-phenylenediamine + anthranilate + NAD+
|
1.7.1.17
FMN-dependent NADH-azoreductase
|
–
|
|
|
BRENDA:
BS440618
|
|
|
|
4''-(diethylamino)-azobenzene-2-carboxylic_acid + 2 NADH + 2 H+ <=> anthranilate + N,N-diethyl-p-phenylenediamine + 2 NAD+
|
1.7.1.17
FMN-dependent NADH-azoreductase
|
–
|
|
|
BRENDA:
BS442877
|
|
|
|
4-dimethylaminoazobenzene-2''-carboxylic_acid + NADH + H+ <=> anthranilate + N,N''-dimethylaminoaniline + NAD+
|
1.7.1.6
azobenzene reductase
|
–
|
|
|
BRENDA:
BS440854
|
|
|
|
Methyl_red + NADH + H+ <=> anthranilate + N,N''-dimethylaminoaniline + NAD+
|
1.7.1.6
azobenzene reductase
|
–
|
|
|
BRENDA:
BS441625
|
|
|
|
ethyl_red + 2 NADH + 2 H+ <=> anthranilate + N,N-diethyl-1,4-phenylenediamine + 2 NAD+
|
1.7.1.17
FMN-dependent NADH-azoreductase
|
–
|
|
|
BRENDA:
BS441376
|
|
|
|
anthranilate + NADH + H+ + O2 <=> 5-hydroxyanthranilate + NAD+ + H2O
|
1.14.13.172
salicylate 5-hydroxylase
|
–
|
|
|
BRENDA:
BS443057
|
|
|
|
N-acetylanthranilate + H2O <=> acetate + anthranilate
|
3.5.1.9
arylformamidase
|
–
|
|
|
BRENDA:
BS140704
|
|
|
|
anthranilonitrile + 2 H2O <=> anthranilate + NH3
|
3.5.5.1
nitrilase
|
–
|
|
|
BRENDA:
BS419251
|
|
|
|
4-dimethylaminoazobenzene-2''-carboxylic_acid + NADPH + H+ <=> anthranilate + N,N''-dimethylamino-aniline + NAD+
|
1.7.1.6
azobenzene reductase
|
–
|
|
|
BRENDA:
BS440855
|
|
|
|
anthranilate + NADPH + O2 <=> 2-Aminophenol + NADP+ + H2O2 + CO2
|
1.14.13.27
4-aminobenzoate 1-monooxygenase
|
–
|
|
|
BRENDA:
BS288399
|
|
|
|
2''-carboxy-4-N,N-dimethylazobenzene + NADH <=> anthranilate + N,N-dimethyl-1,4-phenylenediamine + NADP+
|
1.7.1.6
azobenzene reductase
|
–
|
|
|
BRENDA:
BS260154-a
|
|
|
|
2''-carboxy-4-N,N-dimethylazobenzene + NADPH <=> anthranilate + N,N-dimethyl-1,4-phenylenediamine + NADP+
|
1.7.1.17
FMN-dependent NADH-azoreductase
1.7.1.6
azobenzene reductase
|
–
–
|
|
|
BRENDA:
BS260154
|
|
|
|
2-Aminobenzamide + H2O <=> anthranilate + NH3
|
3.5.1.4
amidase
|
–
|
|
|
BRENDA:
BS383645
|
|
|
|
2-amino-benzonitrile + H2O <=> anthranilate + NH3
|
3.5.5.1
nitrilase
|
–
|
|
|
BRENDA:
BS454895
|
|
|
|
O-methyl_anthranilate + H2O <=> methanol + anthranilate
|
3.1.1.1
carboxylesterase
|
–
|
|
|
BRENDA:
BS363918
|
|
|
|
2 H+ + 2 NADPH + Methyl_red <=> 2 NADP+ + N,N-dimethyl-1,4-phenylenediamine + anthranilate
|
1.7.1.6
azobenzene reductase
|
–
|
|
|
SABIO-RK:
12186
|
|